. . . . . . . "[Our results suggest that apoptosis mediated by OPA1 mutations plays an important role in the pathogenesis of optic atrophy, and both noggin and ?-estrogen may represent potential therapeutic agents for OPA1-related optic atrophy.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:15:07+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .