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[Phosphoinositide 3-kinase, AKT, and the downstream mTOR are involved in cell growth and survival, and they are often found to be activated in mesothelioma. p16(INK4a) and p14(ARF) are frequently inactivated in human mesothelioma, and ?50% of mesotheliomas contain the NF2 mutation.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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