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[Although the initial site of poliovirus replication in humans is the intestine, previously isolated transgenic mice which carry the human poliovirus receptor (PVR) gene (TgPVR mice), which develop poliomyelitis after intracerebral inoculation, are not susceptible to infection by the oral route.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine.
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