http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#head http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://www.nanopub.org/nschema#hasAssertion http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://www.nanopub.org/nschema#hasProvenance http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#provenance http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://www.nanopub.org/nschema#hasPublicationInfo http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://www.nanopub.org/nschema#Nanopublication http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://rdf.disgenet.org/resource/gda/DGNa800d59f89ac5b2a305e19a64f2a728c http://semanticscience.org/resource/SIO_000628 http://identifiers.org/ncbigene/1636 http://rdf.disgenet.org/resource/gda/DGNa800d59f89ac5b2a305e19a64f2a728c http://semanticscience.org/resource/SIO_000628 http://linkedlifedata.com/resource/umls/id/C0151744 http://rdf.disgenet.org/resource/gda/DGNa800d59f89ac5b2a305e19a64f2a728c http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://semanticscience.org/resource/SIO_001122 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#provenance http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://purl.org/dc/terms/description [In the last two decades ACE gene has been cloned that allowed the identification (i) of two isoenzymes, one called somatic ACE resulting from gene duplication and primarily expressed in endothelial cells, and the other, called germinative or testicular ACE, resulting from the transcription in the male reproductive system of a more simple gene, (ii) of an hydrophobic C-terminal peptide for membrane-anchoring and specifically cleaved by a metalloprotease to release soluble forms of both isoenzymes, and (iii) of several allelic polymorphisms, one of them consisting of an insertion/deletion (I/D) polymorphism in a short intronic Alu sequence that could account for half the variance in plasma ACE level and resulting in a large inter-individual variability; moreover this I/D polymorphism was proposed as a genetic marker for identifying individuals at high risk of ischemic heart disease and of anticipating in one individual the efficacy of the antihypertensive therapy, although conflicting data arose from the past decade literature.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine. http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://purl.org/ontology/wi/core#evidence http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://semanticscience.org/resource/SIO_000772 http://identifiers.org/pubmed/12005216 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://www.w3.org/ns/prov#wasDerivedFrom http://rdf.disgenet.org/v5.0.0/void/BEFREE http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#assertion http://www.w3.org/ns/prov#wasGeneratedBy http://purl.obolibrary.org/obo/ECO_0000203 http://rdf.disgenet.org/v5.0.0/void/BEFREE http://purl.org/pav/importedOn 2017-02-19 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/1999/02/22-rdf-syntax-ns#type http://purl.obolibrary.org/obo/ECO_0000212 http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#comment Gene-disease associations inferred from text-mining the literature. http://rdf.disgenet.org/v5.0.0/void/source_evidence_literature http://www.w3.org/2000/01/rdf-schema#label DisGeNET evidence - LITERATURE http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s#publicationInfo http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/dc/terms/created 2017-10-17T13:11:58+02:00 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/dc/terms/rights http://opendatacommons.org/licenses/odbl/1.0/ http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/dc/terms/rightsHolder http://rdf.disgenet.org/v5.0.0/void/IBIGroup http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/dc/terms/subject http://semanticscience.org/resource/SIO_000983 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/net/provenance/ns#usedData http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/authoredBy http://orcid.org/0000-0001-5999-6269 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/authoredBy http://orcid.org/0000-0002-7534-7661 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/authoredBy http://orcid.org/0000-0002-9383-528X http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/authoredBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/authoredBy http://orcid.org/0000-0003-1244-7654 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/createdBy http://orcid.org/0000-0003-0169-8159 http://rdf.disgenet.org/resource/nanopub/NP280577.RAXzdYrkqtmfm1WPSLn25nc1b8jfbQFv4x1DRE7avk72s http://purl.org/pav/version v5.0.0.0 http://rdf.disgenet.org/v5.0.0/void/disgenetv3.0rdf http://purl.org/pav/version v5.0.0