. . . . . . . "[The occurrence and effects of the mutations in APP and the fact that the epsilon 4 allele of ApoE are genetic risk factors point to the hypothesis that the extracellular deposition of beta-amyloid is the key initiating event in the pathogenesis of AD.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:10:36+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .