. . . . . . . "[These drugs are directed against several proinflammatory cytokines (TNF ? , IL-6, and IL-1) which are involved both in the pathogenesis of chronic inflammation and progression of joint structural damage and in systemic and local bone loss typically observed in RA.]. Sentence from MEDLINE/PubMed, a database of the U.S. National Library of Medicine."@en . . . . . "2017-02-19"^^ . . "Gene-disease associations inferred from text-mining the literature."@en . "DisGeNET evidence - LITERATURE"@en . "2017-10-17T13:13:43+02:00"^^ . . . . . . . . . . . "v5.0.0.0" . "v5.0.0" .