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was generated by: activity

abf29
organism name: Homo sapiens
source: CHEBI:15377
source: CHEBI:64689
target: CHEBI:15748
target: CHEBI:168396
type: Interaction

Phase II - Conjugation of compounds

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id775eb3d6
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Tryptophan catabolism leading to NAD+ production

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b32bf
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source: CHEBI:15377
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target: CHEBI:17306
target: CHEBI:17925
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type: Interaction

Digestion

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c92c2
organism name: Homo sapiens
source: CHEBI:15377
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target: R-HSA-5689096
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Deubiquitination

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CHEBI:17855
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is part of: WP1061
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is part of: WP1307
is part of: WP143
is part of: WP145
is part of: WP15
is part of: WP1533
is part of: WP176
is part of: WP1794
is part of: WP1817
is part of: WP1885
organism name: Bos taurus
organism name: Homo sapiens
organism name: Mus musculus
organism name: Rattus norvegicus

ba26b
organism name: Homo sapiens
source: CHEBI:16247
source: CHEBI:17855
source: P04114
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type: Interaction

Plasma lipoprotein assembly, remodeling, and clearance

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b57a4
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Transcriptional regulation by RUNX1

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bd2af
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source: CHEBI:15422
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Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models

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eedc2
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Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

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was generated by: activity

ea50b
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Regulation of mitotic cell cycle

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b9abb
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source: CHEBI:15377
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target: CHEBI:18367
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TBC/RABGAPs

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f6ee1
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target: R-HSA-3322011
target: O95278
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type: Interaction

Glycogen metabolism

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c3148
organism name: Homo sapiens
source: P81605
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type: Interaction

Antimicrobial peptides

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c5970
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source: CHEBI:15377
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target: CHEBI:17754
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Glucose metabolism

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fa8f9
organism name: Homo sapiens
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target: R-HSA-83717
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RNA Polymerase III Transcription

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c0722
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source: R-HSA-4419896
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type: Interaction

Neddylation

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c754b
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source: CHEBI:15378
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Nucleobase biosynthesis

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c4cdb
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target: P00915
type: Interaction

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f5434
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source: R-HSA-6784755
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Interleukin-10 signaling

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de8bf
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Interleukin-6 family signaling

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addc4
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Interleukin-4 and 13 signaling

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d1f40
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source: CHEBI:15453
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Mitochondrial Fatty Acid Beta-Oxidation

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b2096
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source: CHEBI:4026
target: CHEBI:15377
target: CHEBI:18009
target: CHEBI:1864
type: Interaction

Phase I - Functionalization of compounds

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aa215
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source: CHEBI:15422
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target: CHEBI:16761
target: R-HSA-8950252
type: Interaction

Interleukin-12 family signaling

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dd5b0
organism name: Homo sapiens
source: P98082
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target: R-HSA-8862884
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Cargo recognition for clathrin-mediated endocytosis

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dd62b
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Chromatin organization

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ea1e8
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Nucleobase catabolism

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dfa55
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type: Interaction

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eb592
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target: CHEBI:32551
target: R-HSA-6782592
type: Interaction

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f71ff
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source: R-HSA-8855134
target: R-HSA-8855135
type: Interaction

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e0f2f
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source: CHEBI:15377
target: CHEBI:16134
type: Interaction

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was generated by: activity

d2109
organism name: Homo sapiens
source: ENSG00000186891
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target: R-HSA-8877491
type: Interaction

RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)

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e7bd2
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source: CHEBI:15377
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target: CHEBI:15378
target: CHEBI:17154
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type: Interaction

Nicotinate metabolism

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b4b37
organism name: Homo sapiens
source: R-HSA-141440
source: R-HSA-174191
target: R-HSA-141410
type: Interaction

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e6a16
organism name: Homo sapiens
source: P40763
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target: R-HSA-8950427
type: Interaction

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was generated by: activity

fea3a
organism name: Homo sapiens
source: P23468
source: Q9NPH3-1
target: R-HSA-6800384
type: Interaction

Receptor-type tyrosine-protein phosphatases

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dcdf7
organism name: Homo sapiens
source: R-HSA-3371429
source: R-HSA-3371441
source: P31948
target: R-HSA-3371444
target: R-HSA-3371594
type: Interaction

HSP90 chaperone cycle for steroid hormone receptors (SHR)

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was generated by: activity

idcf468dff
organism name: Homo sapiens
source: Q13535
target: Q7Z5Q5
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DNA IR-damage and cellular response via ATR

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Transcriptional regulation by RUNX3

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Fatty acyl-CoA biosynthesis

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Interconversion of nucleotide di- and triphosphates

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Post-translational protein phosphorylation

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Ion channel transport

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Cilium Assembly

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Choline catabolism

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Regulation of RUNX1 Expression and Activity

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RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

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e1d66
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source: CHEBI:15996
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target: CHEBI:17552
target: R-HSA-8875305
target: R-HSA-8877601
type: Interaction

RAB GEFs exchange GTP for GDP on RABs

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was generated by: activity

c377d
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type: Interaction

MAPK signaling pathway

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d7666
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type: Interaction

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aa7a1
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b1e91
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Cellular hexose transport

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bd457
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ff000
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de6ac
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ba902
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source: CHEBI:17002
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type: Interaction

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e1869
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target: CHEBI:83782
type: Interaction

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fe4fc
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target: CHEBI:17985
target: CHEBI:35419
type: Interaction

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fac10
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Keratinization

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d247b
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PTEN Regulation

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caba0
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source: ENST00000344691
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target: R-HSA-8936059
type: Interaction

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ba5d1
organism name: Homo sapiens
source: R-HSA-8951976
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target: R-HSA-8952057
target: Q09472
type: Interaction

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was generated by: activity

c6562
organism name: Homo sapiens
source: CHEBI:15379
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target: CHEBI:27647
type: Interaction

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a8bc6
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target: CHEBI:16680
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type: Interaction

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was generated by: activity

afead
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source: ENSG00000157404
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target: R-HSA-8864692
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Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

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id704faa76
organism name: Homo sapiens
source: Q13535
target: P78527
type: Interaction

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c3180
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target: R-HSA-6783086
type: Interaction

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ce21f
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type: Interaction

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f5059
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target: P48023
type: Interaction

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f1f77
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source: R-HSA-8854160
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target: R-HSA-8855748
type: Interaction

RET signaling

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ec474
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target: Q14765
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a4bab
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target: CHEBI:15846
target: CHEBI:16240
type: Interaction

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dfabe
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target: CHEBI:17118
target: CHEBI:17925
type: Interaction

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c265d
organism name: Homo sapiens
source: P01130
target: P01130
type: Interaction

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af7e5
organism name: Homo sapiens
source: Q13332
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target: R-HSA-6798231
type: Interaction

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was generated by: activity

b0c09
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Triglyceride metabolism

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f82ef
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type: Interaction

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c8c11
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target: CHEBI:27668
type: Interaction

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d8bcd
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target: P01579
type: Interaction

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ddf61
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target: CHEBI:15904
target: CHEBI:16113
type: Interaction

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ff6de
organism name: Homo sapiens
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target: R-HSA-6797291
type: Interaction

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f956d
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source: CHEBI:16863
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target: CHEBI:15378
target: CHEBI:16474
target: CHEBI:16526
target: CHEBI:17363
type: Interaction

Pentose phosphate pathway (hexose monophosphate shunt)

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fc1a7
organism name: Homo sapiens
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target: R-HSA-8876504
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Listeria monocytogenes entry into host cells

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bb3d8
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target: R-HSA-8956549
type: Interaction

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ee507
organism name: Homo sapiens
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target: CHEBI:16761
target: P30304
type: Interaction

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supersedes: RANM6JOd6C6e5Jqe2X2IIUb1SvyhACh39h63oiUtyFklU
was generated by: activity

Q96B97
type: Protein
is part of: WP1910
organism name: Homo sapiens

d7cc6
organism name: Homo sapiens
source: R-HSA-8855235
source: Q96B97
target: R-HSA-8855258
type: Interaction

Reelin signalling pathway

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P16671
type: Protein
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organism name: Homo sapiens

b9755
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type: Interaction

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dbfc1
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source: R-HSA-2025670
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target: R-HSA-2025669
type: Interaction

Collagen chain trimerization

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d3621
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source: R-HSA-8854719
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type: Interaction

Other interleukin signaling

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ea6c6
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type: Interaction

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R-HSA-8865594
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type: Interaction

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e8d8c
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source: R-HSA-8852088
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type: Interaction

Protein ubiquitination

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df014
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type: Interaction

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c9513
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type: Interaction

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f94af
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type: Interaction

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d35d0
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type: Interaction

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idff8c217a
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source: P49760
target: Q13535
type: Interaction

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a8ec9
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type: Interaction

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af110
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type: Interaction

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ecd43
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source: CHEBI:15414
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target: CHEBI:16680
target: R-HSA-8943834
type: Interaction

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was generated by: activity

b83cb
organism name: Homo sapiens
source: R-HSA-204742
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target: R-HSA-8849913
type: Interaction

Synaptic adhesion-like molecules

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bef72
organism name: Homo sapiens
source: R-ALL-174969
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target: R-ALL-174960
target: P18440
type: Interaction

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a7adf
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a1622
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target: R-HSA-8935998
type: Interaction

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f83ea
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target: CHEBI:65135
type: Interaction

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c8566
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type: Interaction

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e07b8
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type: Interaction

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e2869
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target: CHEBI:17925
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fe953
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Fructose metabolism

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ca768
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cd79d
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target: CHEBI:18367
target: CHEBI:29985
type: Interaction

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f2676
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type: Interaction

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a0b4c
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type: Interaction

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bed96
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f25b0
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afb1c
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target: CHEBI:15351
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type: Interaction

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e8512
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type: Interaction

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afb0f
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Regulation of TLR by endogenous ligand

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c08b2
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a423e
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Aryl hydrocarbon receptor signalling

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a1bea
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eeea6
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fbcc2
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b04b4
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type: Interaction

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Neurexins and neuroligins

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Intracellular oxygen transport

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E3 ubiquitin ligases ubiquitinate target proteins

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Lactose synthesis

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aea35
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c4ecd
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a3717
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d2dff
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rRNA modification in the mitochondrion

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fa46a
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bd520
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Signaling by MET

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Butyrophilin (BTN) family interactions

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Intestinal absorption

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a2691
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cccec
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source: CHEBI:15414
source: P11142
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type: Interaction

Protein methylation

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f62da
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type: Interaction

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e8b9d
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c2fef
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target: CHEBI:17202
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type: Interaction

Nucleotide salvage

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ae036
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b8bc9
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c17c4
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ceb43
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fdcda
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f86b9
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cb2be
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type: Interaction

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a08d9
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c18ab
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e94c4
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fafc9
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f3901
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ad486
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type: Interaction

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f1042
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type: Interaction

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ab587
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bc0dd
organism name: Homo sapiens
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b7f74
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target: CHEBI:16842
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type: Interaction

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d5812
organism name: Homo sapiens
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de5dc
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bd39e
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dda22
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b3be6
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target: CHEBI:43263
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dc8ab
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d3661
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c37f6
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c3d6d
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Clathrin-mediated endocytosis

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da7e2
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ed27b
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c3c48
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fbcbf
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b2c54
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a60ef
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c867c
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f82cf
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e11ad
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f81b7
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PTF1A related regulatory pathway

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Mitochondrial Unfolded-Protein Response (UPRmt)

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Senescence and Autophagy in Cancer

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Estrogen metabolism

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Monoamine Transport

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Serotonin Receptor 4/6/7 and NR3C Signaling

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Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways

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Serotonin Receptor 2 and STAT3 Signaling

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Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

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DNA Damage Response

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TCA Cycle

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DNA Damage Response (only ATM dependent)

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id61d4ba12
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MAPK Signaling Pathway

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c377d
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MAPK Signaling Pathway

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id68dda630
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TCA Cycle

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R-HSA-5689624
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Nucleotide Excision Repair

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Selenium Micronutrient Network

Eicosanoid Synthesis

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R-HSA-173749
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Complement cascade

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Sterol Regulatory Element-Binding Proteins (SREBP) signalling

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AMP-activated Protein Kinase (AMPK) Signaling

Target Of Rapamycin (TOR) Signaling

Angiogenesis

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Statin Pathway

Folate Metabolism

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O75521-2
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Peroxisomal lipid metabolism

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R-HSA-72069
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Processing of Capped Intron-Containing Pre-mRNA

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Eukaryotic Translation Elongation

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R-HSA-211223
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Apoptotic execution phase

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Fatty acid, triacylglycerol, and ketone body metabolism

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K01G5.7
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Cell Division: First embryonic mitosis

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Apoptosis

Signal Transduction of S1P Receptor

VEGFR-3 signaling

VEGF-receptor Signal Transduction

Genetic alterations of lung cancer

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Vitamin B12 Metabolism

Folate Metabolism

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P05141
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Integration of energy metabolism

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One Carbon Metabolism

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T10B5.6
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Y47G6A.24
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Response to elevated platelet cytosolic Ca2+

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R-HSA-517938
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Circadian Clock

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R-HSA-113815
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ENSG00000138207
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O00337
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Transport of vitamins, nucleosides, and related molecules

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R-HSA-5653761
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DNA Damage Bypass

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Glutathione metabolism

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C29E4.8
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ENSBTAG00000000283
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http://identifiers.org/ncbigene/2352
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Selenium metabolism/Selenoproteins

TGF Beta Signaling Pathway

Estrogen signaling

SIDS Susceptibility Pathways

Oxidative Damage

IL-5 Signaling Pathway

MicroRNAs in Cardiomyocyte Hypertrophy

Apoptosis Modulation by HSP70

PluriNetWork

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C45G3.3
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R-HSA-8964582
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Mitotic G1-G1/S phases

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R-HSA-5655479
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R-ALL-377604
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Integrin alphaIIb beta3 signaling

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R-HSA-166719
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Apoptosis

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R-HSA-8850528
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Protein folding

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R-HSA-110279
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P21926
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Integrated Breast Cancer Pathway

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R-HSA-418977
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Cell junction organization

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DNA Damage Reversal

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TNF alpha Signaling Pathway

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R-HSA-5655177
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F32H2.3
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R-HSA-606288
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Nucleosome assembly

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ACE Inhibitor Pathway

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Unfolded Protein Response (UPR)

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Vitamin D Metabolism

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One Carbon Metabolism

One Carbon Metabolism

One Carbon Metabolism

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Methylation

Methylation

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Selenium Metabolism and Selenoproteins

Selenium metabolism Selenoproteins

Selenium metabolism Selenoproteins

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P12235
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Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

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Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)

PPAR Alpha Pathway

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One Carbon Metabolism

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MyD88 dependent cascade initiated on endosome

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Mitochondrial protein import

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Alzheimers Disease

Serotonin and anxiety

Spinal Cord Injury

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PIP3 activates AKT signaling

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Seed Development

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Iron metabolism in placenta

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ATM Signaling Pathway

PDGF Pathway

T-Cell Receptor and Co-stimulatory Signaling

Structural Pathway of Interleukin 1 (IL-1)

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Signaling by the B Cell Receptor (BCR)

Fc epsilon receptor (FCERI) signaling

Cytosolic sensors of pathogen-associated DNA

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Signaling by NOTCH2

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Fatty Acid Omega Oxidation

Aryl Hydrocarbon Receptor

Nuclear Receptors in Lipid Metabolism and Toxicity

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AT3G43190
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AT1G33260
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R-HSA-2981043
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Binding and Uptake of Ligands by Scavenger Receptors

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ENSG00000125257
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Ectoderm Differentiation

Pregnane X Receptor pathway

NRF2 pathway

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Mecp2 and Associated Rett Syndrome

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Role of lipid metabolism in C. elegans

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Notch signaling in Vulval Development

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R-HSA-188132
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Toll-Like Receptors Cascades

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ER Stress-Unfolded Protein Response (UPRer)

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Neural Crest Differentiation

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Aryl Hydrocarbon Receptor Pathway

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Glycerophospholipid biosynthesis

Visual phototransduction

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AT4G14150
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R-HSA-2028630
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Signaling by Hippo

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AT5G03650
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AT5G56080
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R-HSA-4395237
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Pre-NOTCH Expression and Processing

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R-CBO-5228686
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Neurotoxicity of clostridium toxins

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PI Metabolism

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P08311
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Metabolism of Angiotensinogen to Angiotensins

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Neural Crest Differentiation

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AT1G56560
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MIMAT0000539
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R-HSA-8865622
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Interleukin-7 signaling

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Estrogen Receptor Pathway

Selenium Metabolism and Selenoproteins

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Drug Induction of Bile Acid Pathway

Farnesoid X Receptor Pathway

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Glycerophospholipid Biosynthetic Pathway

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AT4G32260
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O14735
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R-HSA-2559461
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R-HSA-5674360
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RAF/MAP kinase cascade

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Mitotic Prometaphase

Meiotic synapsis

Mitotic Metaphase and Anaphase

Mitotic Telophase/Cytokinesis

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AT4G25000
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CHEBI:49086
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R-HSA-5660440
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Activation of gene expression by SREBF (SREBP)

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R-HSA-1604469
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Signaling by NOTCH1

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AT1G77670
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CHEBI:17555
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P15056
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C34E10.6
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Male mating

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R-HSA-975133
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ENSG00000087088
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Nanomaterial induced apoptosis

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ENSG00000105697
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Iron metabolism in placenta

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R-HSA-264684
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Lipid digestion, mobilization, and transport

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Spinal Cord Injury

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R-HSA-921123
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Gastrin-CREB signalling pathway via PKC and MAPK

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AT5G17990
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Constitutive Androstane Receptor Pathway

Vitamin D Receptor Pathway

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Serotonin and anxiety-related events

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Signaling by TGF-beta Receptor Complex

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Cell Differentiation - Index expanded

Cell Differentiation - Index

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Regulation of mRNA stability by proteins that bind AU-rich elements

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MyD88-independent TLR3/TLR4 cascade

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Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

MyD88 cascade initiated on plasma membrane

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Allograft Rejection

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Liver X Receptor Pathway

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Bladder Cancer

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Adipogenesis

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Mitotic Prophase

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Detoxification of Reactive Oxygen Species

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Gamma carboxylation, hypusine formation and arylsulfatase activation

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created: 2018-06-09T11:20:23.561+02:00
rights: http://creativecommons.org/publicdomain/zero/1.0/
supersedes: RAWzwOtBbeRj3hvFZUSz5jFgu8j0IORRPcgH0XFIbkSXg
was generated by: activity