Phase II - Conjugation of compounds

Tryptophan catabolism leading to NAD+ production

Digestion

Deubiquitination

Plasma lipoprotein assembly, remodeling, and clearance

Transcriptional regulation by RUNX1

Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models

Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation

Regulation of mitotic cell cycle

TBC/RABGAPs

Glycogen metabolism

Antimicrobial peptides

Glucose metabolism

RNA Polymerase III Transcription

Neddylation

Nucleobase biosynthesis

Interleukin-10 signaling

Interleukin-6 family signaling

Interleukin-4 and 13 signaling

Mitochondrial Fatty Acid Beta-Oxidation

Phase I - Functionalization of compounds

Interleukin-12 family signaling

Cargo recognition for clathrin-mediated endocytosis

Chromatin organization

Nucleobase catabolism

RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)

Nicotinate metabolism

Receptor-type tyrosine-protein phosphatases

HSP90 chaperone cycle for steroid hormone receptors (SHR)

DNA IR-damage and cellular response via ATR

Transcriptional regulation by RUNX3

Fatty acyl-CoA biosynthesis

Interconversion of nucleotide di- and triphosphates

Post-translational protein phosphorylation

Ion channel transport

Cilium Assembly

Choline catabolism

Regulation of RUNX1 Expression and Activity

RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function

RAB GEFs exchange GTP for GDP on RABs

MAPK signaling pathway

Cellular hexose transport

Keratinization

PTEN Regulation

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors

RET signaling

Triglyceride metabolism

Pentose phosphate pathway (hexose monophosphate shunt)

Listeria monocytogenes entry into host cells

Reelin signalling pathway

Collagen chain trimerization

Other interleukin signaling

Protein ubiquitination

Synaptic adhesion-like molecules

Fructose metabolism

Regulation of TLR by endogenous ligand

Aryl hydrocarbon receptor signalling

Neurexins and neuroligins

Intracellular oxygen transport

E3 ubiquitin ligases ubiquitinate target proteins

Lactose synthesis

rRNA modification in the mitochondrion

Signaling by MET

Butyrophilin (BTN) family interactions

Intestinal absorption

Protein methylation

Nucleotide salvage

Clathrin-mediated endocytosis

EMT transition in Colorectal Cancer

Endometrial cancer

MTF1 activates gene expression

PTF1A related regulatory pathway

NADPH regeneration

Mitochondrial calcium ion transport

Cristae formation

Mitochondrial Unfolded-Protein Response (UPRmt)

ACE Inhibitor Pathway

Senescence and Autophagy in Cancer

Estrogen metabolism

Monoamine Transport

Serotonin Receptor 4/6/7 and NR3C Signaling

Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways

Serotonin Receptor 2 and STAT3 Signaling

Serotonin Receptor 2 and ELK-SRF/GATA4 signaling

DNA Damage Response

TCA Cycle

DNA Damage Response (only ATM dependent)

MAPK Signaling Pathway

Nucleotide Excision Repair

Selenium Micronutrient Network

Eicosanoid Synthesis

Complement cascade

Sterol Regulatory Element-Binding Proteins (SREBP) signalling

AMP-activated Protein Kinase (AMPK) Signaling

Target Of Rapamycin (TOR) Signaling

Angiogenesis

Statin Pathway

Folate Metabolism

Peroxisomal lipid metabolism

Processing of Capped Intron-Containing Pre-mRNA

Eukaryotic Translation Elongation

Apoptotic execution phase

Fatty acid, triacylglycerol, and ketone body metabolism

Cell Division: First embryonic mitosis

Apoptosis

Signal Transduction of S1P Receptor

VEGFR-3 signaling

VEGF-receptor Signal Transduction

Genetic alterations of lung cancer

Vitamin B12 Metabolism

Integration of energy metabolism

One Carbon Metabolism

Response to elevated platelet cytosolic Ca2+

Circadian Clock

Transport of vitamins, nucleosides, and related molecules

DNA Damage Bypass

Glutathione metabolism

Selenium metabolism/Selenoproteins

TGF Beta Signaling Pathway

Estrogen signaling

SIDS Susceptibility Pathways

Oxidative Damage

IL-5 Signaling Pathway

MicroRNAs in Cardiomyocyte Hypertrophy

Apoptosis Modulation by HSP70

PluriNetWork

Mitotic G1-G1/S phases

Integrin alphaIIb beta3 signaling

Cell surface interactions at the vascular wall

Formation of Fibrin Clot (Clotting Cascade)

Calcium Regulation in the Cardiac Cell

Oxidative phosphorylation

Photosynthetic Carbon Reduction

DNA Replication

Folic Acid Network

Serotonin Transporter Activity

Regulation of toll-like receptor signaling pathway

MicroRNAs in cardiomyocyte hypertrophy

Cell Cycle Checkpoints

Mitotic G2-G2/M phases

Type II interferon signaling (IFNG)

Metabolism of water-soluble vitamins and cofactors

Aflatoxin B1 metabolism

Regulation of DNA replication

Synthesis of DNA

Sphingolipid Metabolism

Protein folding

Integrated Breast Cancer Pathway

Cell junction organization

DNA Damage Reversal

TNF alpha Signaling Pathway

Nucleosome assembly

Unfolded Protein Response (UPR)

Vitamin D Metabolism

Methylation

Selenium Metabolism and Selenoproteins

Selenium metabolism Selenoproteins

NGF signalling via TRKA from the plasma membrane

Signaling by Insulin receptor

Eukaryotic Translation Initiation

Signaling by VEGF

Metapathway Signal Transduction

Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Processing of Capped Intronless Pre-mRNA

RNA Polymerase II Transcription

Vitamin A and Carotenoid Metabolism

Retinol metabolism

Intrinsic Pathway for Apoptosis

GPCR ligand binding

Fluoropyrimidine Activity

Opioid Signalling

Folate-Alcohol and Cancer Pathway Hypotheses

Arachidonate Epoxygenase Epoxide Hydrolase

Fatty Acid Beta Oxidation

Platelet homeostasis

Signaling by PDGF

Signaling by EGFR

Transport of glycerol from adipocytes to the liver by Aquaporins

Wnt Signaling Pathway and Pluripotency

Transport of inorganic cations/anions and amino acids/oligopeptides

EPO Receptor Signaling

IL-6 Signaling Pathway

Kit Receptor Signaling Pathway

TNF-alpha and mucus production in lung epythelium

Focal Adhesion

Electron Transport Chain

Endochondral Ossification

Oxidation by Cytochrome P450

Heme Biosynthesis

Effects of Nitric Oxide

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)

Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)

PPAR Alpha Pathway

MyD88 dependent cascade initiated on endosome

Mitochondrial protein import

Alzheimers Disease

Serotonin and anxiety

Spinal Cord Injury

PIP3 activates AKT signaling

Seed Development

Iron metabolism in placenta

ATM Signaling Pathway

PDGF Pathway

T-Cell Receptor and Co-stimulatory Signaling

Structural Pathway of Interleukin 1 (IL-1)

TAK1 activates NFkB by phosphorylation and activation of IKKs complex

Signaling by the B Cell Receptor (BCR)

Fc epsilon receptor (FCERI) signaling

Cytosolic sensors of pathogen-associated DNA

Signaling by NOTCH2

Fatty Acid Omega Oxidation

Aryl Hydrocarbon Receptor

Nuclear Receptors in Lipid Metabolism and Toxicity

Binding and Uptake of Ligands by Scavenger Receptors

Ectoderm Differentiation

Pregnane X Receptor pathway

NRF2 pathway

Mecp2 and Associated Rett Syndrome

Role of lipid metabolism in C. elegans

Notch signaling in Vulval Development

Toll-Like Receptors Cascades

ER Stress-Unfolded Protein Response (UPRer)

Neural Crest Differentiation

Aryl Hydrocarbon Receptor Pathway

Glycerophospholipid biosynthesis

Visual phototransduction

Signaling by Hippo

Pre-NOTCH Expression and Processing

Neurotoxicity of clostridium toxins

PI Metabolism

Metabolism of Angiotensinogen to Angiotensins

Interleukin-7 signaling

Estrogen Receptor Pathway

Drug Induction of Bile Acid Pathway

Farnesoid X Receptor Pathway

Glycerophospholipid Biosynthetic Pathway

RAF/MAP kinase cascade

Mitotic Prometaphase

Meiotic synapsis

Mitotic Metaphase and Anaphase

Mitotic Telophase/Cytokinesis

Activation of gene expression by SREBF (SREBP)

Signaling by NOTCH1

Male mating

Nanomaterial induced apoptosis

Lipid digestion, mobilization, and transport

Gastrin-CREB signalling pathway via PKC and MAPK

Constitutive Androstane Receptor Pathway

Vitamin D Receptor Pathway

Serotonin and anxiety-related events

Signaling by TGF-beta Receptor Complex

Cell Differentiation - Index expanded

Cell Differentiation - Index

Regulation of mRNA stability by proteins that bind AU-rich elements

MyD88-independent TLR3/TLR4 cascade

MyD88:Mal cascade initiated on plasma membrane

Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways

MyD88 cascade initiated on plasma membrane

Allograft Rejection

Primary Focal Segmental Glomerulosclerosis FSGS

Liver X Receptor Pathway

Bladder Cancer

Adipogenesis

Mitotic Prophase

Detoxification of Reactive Oxygen Species

Gamma carboxylation, hypusine formation and arylsulfatase activation

SUMOylation

Abacavir transport and metabolism

M/G1 Transition

Biosynthesis and regulation of nematode bile acids

Deadenylation-dependent mRNA decay

Cytokinin-Auxin interactions in plant development

Regulation of cholesterol biosynthesis by SREBP (SREBF)

Trafficking and processing of endosomal TLR
EGF Signaling in Vulval Development
Host Interactions of HIV factors
DAP12 interactions
Signaling by SCF-KIT
One carbon donor
Trans-sulfuration and one carbon metabolism
HIV Life Cycle
ISG15 antiviral mechanism
Influenza Life Cycle
Metabolism of non-coding RNA
Host Interactions with Influenza Factors
TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway
De Novo Biosynthesis of Purine Nucleotides
Carbon monoxide dehydrogenase pathway
Common Pathways Underlying Drug Addiction
Regulation of immune response in the intestine
Aging
Cytokinin signaling
Metabolism of steroid hormones
GABA synthesis, release, reuptake and degradation
Immune responses in the epidermis
Arachidonic acid metabolism
Cardiolipin Biosynthesis
Flowering Time Pathway
Translocation of GLUT4 to the plasma membrane
Signaling by NODAL
Defensins
Mitochondrial iron-sulfur cluster biogenesis
Signaling Pathways in Glioblastoma
Differentiation Pathway
EBV LMP1 signaling
Erythrocytes take up oxygen and release carbon dioxide
Erythrocytes take up carbon dioxide and release oxygen