Homo sapiens

dihydrotestosterone

Recon 2.2: from reconstruction to model of human metabolism

androstenedione

pregnenolone

sebacic acid

azelaic acid

erucic acid

carnosine

sarcosine

norharman

tolbutamide

Vasoactive intestinal peptide

UniProt

estrone

lanosterol

antipyrine

L-kynurenine

umbelliferone

gondoic acid

picolinic acid

12-O-tetradecanoylphorbol-13-acetate

WikiPathways

L-homoserine

NGB

ensembl Release 94

malondialdehyde

pentadecanoic acid

deoxyuridine

GIP

Ecgonine

galactitol

dinoprost

2-aminoethylphosphonic acid

Trehalose

malonic acid

retinal

17β-estradiol

2'-deoxyadenosine

guanosine

thymidine

androsterone

2'-deoxyguanosine

Deoxycytidine

guanosine cyclic 3',5'-phosphate

cytidine

corticosterone

inosine

uridine

cortisone

L-xylulose

brussels sprouts

Sinigrin

deoxyguanosine triphosphate

D-xylulose 5-phosphate(2-)

dCTP

retinol

phenylacetaldehyde

silibinin a

Norcodeine (stereochemistry defined)

all-cis-docosa-7,10,13,16-tetraenoic acid

16alpha-hydroxydehydroepiandrosterone

2-methoxyestradiol

3,4-dihydroxymandelic acid

3,4-dihydroxyphenylacetaldehyde

7alpha-hydroxycholest-4-en-3-one

aflatoxin B1

Ap4A

L-Leucine

L-Valine

N-acetylserotonin

L-Isoleucine

L-Histidine

Chaetomium globosum

koningic acid

Specific inhibition of glyceraldehyde-3-phosphate dehydrogenase by koningic acid (heptelidic acid)

Trichoderma koningii

Gliocladium virens

Anthostoma avocetta

Cytochalasin B

Dihydrobiopterin

dodecanedioic acid

etiocholanolone

olive fruit fly

(S)-1,7-Dioxaspiro[5.5]undecane

Sex-specific activity of (R)-(-)- and (S)-(+)-1,7-dioxaspiro[5.5]undecane, the major pheromone of Dacus oleae

(R)-1,7-Dioxaspiro[5.5]undecane

phosphocholine

house mouse

ChEBI

Taphrorychus bicolor

(1S,2R,5R)-2-Ethyl-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane

Synthesis of (1S,2R,5R)-2-Ethyl-1,5-dimethyl-6,8-dioxabicyclo[3.2.1]octane, the Aggregation Pheromone of Male Beech Bark Beetles,Taphrorychus bicolor (Col., Scol.)

Myrmicaria natalensis eumenoides

(+)-Myrmicarin 237B

New alkaloids from ants: Identification and synthesis of (3R,5S,9R)-3-butyl-5-(1-oxopropyl)indolizidine and (3R,5R,9R)-3-butyl-5-(1-oxopropyl)indolizidine, constituents of the poison gland secretion in Myrmicaria eumenoides (hymenoptera, formicidae)

(3R,5S,9R)‐3‐butyl‐5‐(1‐oxopropyl)indolizidine

Heme B

glycine

leukotriene D4

3α-androstanediol

diglycine

acetimidoquinone

pregnenolone sulfate

(±)-adrenaline

DL-3,3',5'-triiodothyronine

thiamine ion

N-methylserotonin

biocytin

suberic acid

glycolaldehyde

homovanillic acid

methylglyoxal

dihydroxyindole

desoxycortone

4-hydroxyphenyl acetaldehyde

keto-D-fructose 1-phosphate

methanol

adenine

carbon dioxide

carbon monoxide

sodium chloride

hydrogen cyanide

Prunus armeniaca

progesterone

fibrin

water

flavin adenine dinucleotide

D-ribulose

LXB4

cholesterol

N,N-dimethylglycine

urea

acetone

xanthine

thiocyanate

acetaldehyde

Arabidopsis thaliana

quercitrin

File 1. Profiling of floral secondary metabolites in Arabidopsis accessions.

Quercetin 3,7-diglucoside

Isorhamnetin 3-glucoside

Kaempferol 3,7-diglucoside

Quercetin 3,7-dirhamnoside

neoglucobrassicin

4-methoxyglucobrassicin

glucoalyssin

glucoerucin(1-)

glucoiberin

sophoraflavonoloside

quercetin 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside

Glucolesquerellin

7-Methylthioheptyl glucosinolate

8-Methylthiooctyl glucosinolate

Glucohirsutin

afzelin

Isorhamnetin 3-O-beta-glucopyranoside-7-O-alpha-rhamnopyranoside

Glucoraphanin

Quercetin 3-O-glucoside-7-O-rhamnoside

glucohesperin

glucoibarin

isoquercetin

lespedin

glucobrassicin

Wikidata Metabolite-Species Nanopublications, version 20190113_0951

Nanopublications based on statements in Wikidata that specify in which species a particular molecule acts as metabolite, including reference on which that statement is based.

Nanopubs covering complexes extracted from WikiPathways version 20190310

Nanopubs covering interactions extracted from WikiPathways version 20190310

Nanopubs covering pathwayParticipation extracted from WikiPathways version 20190310

Nanopublications extracted from WikiPathways, incremental dataset, 20190310

Statin Pathway

The alternative pathway of fetal androgen synthesis

Integrin-mediated Cell Adhesion

MAPK Signaling Pathway

Composition of Lipid Particles

Classical pathway of steroidogenesis, including diseases

Oxysterols derived from cholesterol

Carnosine's role in mucle contraction

ncRNAs involved in Wnt signaling in hepatocellular carcinoma

Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases

Metabolic pathway of LDL, HDL and TG, including diseases

Glycosylation and related congenital defects.

Cerebral Organic Acidurias, including diseases

Folate Metabolism

Nuclear receptors in lipid metabolism and toxicity

Vitamin D Metabolism

Vitamin B12 Metabolism

Selenium Micronutrient Network

Sterol Regulatory Element-Binding Proteins (SREBP) signalling

Wnt Signaling Pathway and Pluripotency

Wnt Signaling Pathway

Vitamin A and Carotenoid Metabolism

Osteoblast Signaling

Retinol metabolism

ACE Inhibitor Pathway

Calcium Regulation in the Cardiac Cell

G Protein Signaling Pathways

Folic Acid Network

AMP-activated Protein Kinase (AMPK) Signaling

Physiological and Pathological Hypertrophy of the Heart

FGF signaling pathway

MicroRNAs in cardiomyocyte hypertrophy

MicroRNAs in Cardiomyocyte Hypertrophy

Type II diabetes mellitus

Nicotine Activity on Dopaminergic Neurons

Nicotine Activity on Chromaffin Cells

Apoptosis Modulation and Signaling

IL-1 signaling pathway

Fatty Acid Beta Oxidation

Cell surface interactions at the vascular wall

Platelet homeostasis

SREBP signalling

Drug Induction of Bile Acid Pathway

Biochemical Pathways Part I

AtMetExpress overview

Lipid Droplet Metabolism

Mevalonate pathway

RANKL/RANK Signaling Pathway

Dopamine metabolism

Amyotrophic lateral sclerosis (ALS)

Oxidative Stress Induced Senescence

DNA Double Strand Break Response

DNA Damage/Telomere Stress Induced Senescence

Lung fibrosis

Parkinsons Disease Pathway

Ethanol effects on histone modifications

MECP2 and Associated Rett Syndrome

ESC Pluripotency Pathways

Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation

VEGFA-VEGFR2 Signaling Pathway

Focal Adhesion

IL-6 signaling pathway

TGF-beta Signaling Pathway

Melatonin metabolism and effects

Retinoid metabolism and transport

EV release from cardiac cells and their functional effects

ApoE and miR-146 in inflammation and atherosclerosis

POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation

Focal Adhesion-PI3K-Akt-mTOR-signaling pathway

Prostaglandin Synthesis and Regulation

AMPK Signaling

Endothelin Pathways

Cardiac Hypertrophic Response

T-Cell Receptor and Co-stimulatory Signaling

MFAP5-mediated ovarian cancer cell motility and invasiveness

Renin - Angiotensin System

Wnt Signaling in Kidney Disease

T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection

Cannabinoid receptor signaling

Angiotensin II signaling (acute) in thick ascending limbs

Lipid Metabolism Pathway

Effect of L-carnitine on metabolism

Endometrial cancer

PI3K-Akt Signaling Pathway

Ras Signaling

Non-small cell lung cancer

Breast cancer pathway

Pancreatic adenocarcinoma pathway

Viral Acute Myocarditis

Synaptic signaling pathways associated with autism spectrum disorder

SUMOylation of intracellular receptors

Transcriptional regulation by RUNX2

Biosynthesis of DHA-derived SPMs

Peroxisomal protein import

NO/cGMP/PKG mediated Neuroprotection

Sulfate assimilation and copper detoxification

Vitamin B12 Disorders

Oxidation by Cytochrome P450

Signaling by Retinoic Acid

Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation

Synthesis of Lipoxins (LX)

Biosynthesis of DPA-derived SPMs

Biosynthesis of EPA-derived SPMs

Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives

Steroid Biosynthesis

Ferroptosis

Histone Modifications

MTHFR deficiency

Integrated Breast Cancer Pathway

miRNA Regulation of DNA Damage Response

SRF and miRs in Smooth Muscle Differentiation and Proliferation

Heart Development

miRNAs involved in DNA damage response

Integrated Cancer Pathway

Fluoropyrimidine Activity

Eicosanoid Synthesis

Pre-NOTCH Expression and Processing

Activation of gene expression by SREBF (SREBP)

Retinoblastoma Gene in Cancer

Cellular response to heat stress

Iron uptake and transport

NoRC negatively regulates rRNA expression

TP53 Regulates Metabolic Genes

Eicosanoid metabolism via Lipo Oxygenases (LOX)

Cysteine and methionine catabolism

Eicosanoid metabolism via Cyclo Oxygenases (COX)

Cholesterol metabolism (includes both Bloch and Kandutsch-Russell pathways)

Butyrophilin (BTN) family interactions

Molybdenum cofactor (Moco) biosynthesis

Tyrosine Metabolism

Target Of Rapamycin (TOR) Signaling

Regulation of toll-like receptor signaling pathway

Angiogenesis

TP53 Network

L1CAM interactions

Signaling by EGFR

Arachidonate Epoxygenase / Epoxide Hydrolase

Arachidonate Epoxygenase Epoxide Hydrolase

Glutathione metabolism

Matrix Metalloproteinases

Costimulation by the CD28 family

Intrinsic Pathway for Apoptosis

Metabolism of nitric oxide

Mitotic G1-G1/S phases

Signaling by VEGF

Apoptotic execution phase

DDX58/IFIH1-mediated induction of interferon-alpha/beta

Serotonin Transporter Activity

Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)

PPAR Alpha Pathway

Nuclear Receptors Meta-Pathway

Aryl Hydrocarbon Receptor Pathway

Constitutive Androstane Receptor Pathway

Pregnane X Receptor pathway

NRF2 pathway

Signaling Pathways in Glioblastoma

Allograft Rejection

Spinal Cord Injury

Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)

Endoderm Differentiation

Ectoderm Differentiation

Hematopoietic Stem Cell Differentiation

ATM Signaling Pathway

Heroin metabolism

Estrogen Receptor Pathway

Selenium Metabolism and Selenoproteins

miRs in Muscle Cell Differentiation

Cell Differentiation - Index expanded

Cell Differentiation - Index

Cardiac Progenitor Differentiation

Trans-sulfuration pathway

One Carbon Metabolism

Trans-sulfuration and one carbon metabolism

Nanomaterial induced apoptosis

Gluconeogenesis

Superpathway of pyridoxal 5'-phosphate biosynthesis and salvage

Primary Carbon Metabolism

Glycolysis

Mecp2 and Associated Rett Syndrome

Neural Crest Differentiation

Primary Focal Segmental Glomerulosclerosis FSGS

Mammary gland development pathway - Puberty (Stage 2 of 4)

Human Thyroid Stimulating Hormone (TSH) signaling pathway

IL-7 Signaling Pathway

Oncostatin M Signaling Pathway

Aryl Hydrocarbon Receptor

Apoptosis-related network due to altered Notch3 in ovarian cancer

Vitamin D Receptor Pathway

Mammary gland development pathway - Embryonic development (Stage 1 of 4)

Dopaminergic Neurogenesis

Lidocaine metabolism

Felbamate Metabolism

Cocaine metabolism

Alzheimers Disease

EBV LMP1 signaling

Notch Signaling

Signaling by NOTCH2

Signaling by NOTCH1

Signaling by NOTCH4

Signaling by NOTCH3

Gene regulatory network modelling somitogenesis

Gastric Cancer Network 2

Apoptosis

Mammary gland development pathway - Involution (Stage 4 of 4)

Bladder Cancer

HIV Life Cycle

Signaling by NODAL

Signaling by TGF-beta Receptor Complex

Gamma carboxylation, hypusine formation and arylsulfatase activation

Sulindac Metabolic Pathway

SREBF and miR33 in cholesterol and lipid homeostasis

Differentiation of white and brown adipocyte

Hair Follicle Development: Cytodifferentiation (Part 3 of 3)

ATF4 activates genes

Calvin cycle

Metastatic brain tumor

Prolactin Signaling Pathway

Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway

B Cell Receptor Signaling Pathway

Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer

Regulation of cholesterol biosynthesis by SREBP (SREBF)

Parkin-Ubiquitin Proteasomal System pathway

Structural Pathway of Interleukin 1 (IL-1)

Degradation of beta-catenin by the destruction complex

Human Complement System

Mesodermal Commitment Pathway

Regulation of Microtubule Cytoskeleton

Mitotic Prophase

Meiotic recombination

Meiotic synapsis

TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway

TNF alpha Signaling Pathway

Adipogenesis

Folate-Alcohol and Cancer Pathway

One carbon donor

Methionine De Novo and Salvage Pathway

Amino Acid metabolism

One carbon metabolism and related pathways

Nonhomologous End-Joining (NHEJ)

Circadian rhythm related genes

DNA IR-Double Strand Breaks (DSBs) and cellular response via ATM

SUMOylation of DNA replication proteins

Mitochondrial biogenesis

SIRT1 negatively regulates rRNA expression

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)

Hedgehog 'off' state

TCF dependent signaling in response to WNT

B-WICH complex positively regulates rRNA expression

BMAL1:CLOCK,NPAS2 activates circadian gene expression

SUMOylation of DNA damage response and repair proteins

Resolution of Abasic Sites (AP sites)

Mismatch Repair

Fanconi Anemia Pathway

Regulation of TP53 Activity through Phosphorylation

Copper homeostasis

Hepatitis C and Hepatocellular Carcinoma

ERK Pathway in Huntington's Disease

Oxidative Damage

Prion disease pathway

PDGF Pathway

Oxytocin signaling

RHO GTPases activate IQGAPs

RHO GTPases activate PAKs

C-type lectin receptors (CLRs)

Uptake and function of anthrax toxins

Synthesis, secretion, and deacylation of Ghrelin

Amyloid fiber formation

Beta-catenin independent WNT signaling

BDNF-TrkB Signaling

Cell-type Dependent Selectivity of CCK2R Signaling

Association Between Physico-Chemical Features and Toxicity Associated Pathways

Striated Muscle Contraction

Cardiac conduction

Serotonin and anxiety

GPR40 Pathway

Prader-Willi and Angelman Syndrome

tRNA processing in the nucleus

Gene Silencing by RNA

SUMOylation of RNA binding proteins

SUMOylation of chromatin organization proteins

Regulation of TP53 Activity through Acetylation

SIDS Susceptibility Pathways

Arrhythmogenic Right Ventricular Cardiomyopathy

Myometrial Relaxation and Contraction Pathways

RAC1/PAK1/p38/MMP2 Pathway

Transcription factor regulation in adipogenesis

Hypothesized Pathways in Pathogenesis of Cardiovascular Disease

RIG-I-like Receptor Signaling

Canonical and Non-Canonical TGF-B signaling

PDGFR-beta pathway

Overview of nanoparticle effects

Aflatoxin activation and detoxification

Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism

Sulfur amino acid metabolism

Selenoamino acid metabolism

ATR Signaling

Oncogene Induced Senescence

Regulation of TP53 Activity through Association with Co-factors

TP53 Regulates Transcription of Cell Death Genes

TP53 Regulates Transcription of Cell Cycle Genes

Regulation of TP53 Expression and Degradation

TP53 Regulates Transcription of DNA Repair Genes

Regulation of TP53 Activity through Methylation

SUMOylation of transcription factors

mTOR signalling

Regulation of beta-cell development

Class I MHC mediated antigen processing & presentation

PRC2 methylates histones and DNA

DNA methylation

Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3

ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression

Activation of anterior HOX genes in hindbrain development during early embryogenesis

Eicosanoid metabolism via Cytochrome P450 Mono-Oxygenases (CYP) pathway

Purine metabolism

Pyrimidine metabolism and related diseases

White fat cell differentiation

Phosphodiesterases in neuronal function

Thermogenesis

Transcriptional Regulation by MECP2

Eicosanoid Lipid Synthesis Map